Prostate drugs make erectile dysfunction worse

53.85% credibility
 
Related

Brazil's Ex-Leader, Luiz Inácio Lula da Silva, Is Held for Questioning

Atma
824 points

A mom wrote a heartwarming letter to Hillary Clinton about her dreams for her daughter s future

Atma
772 points



Most recent

El secreto del cambio

El diario de Enrique
12 points

A ver si me lo igualáis

El diario de Enrique
8 points

INDIGNACION POR ASONADA A SOLDADOS EN EL CAUCA

Carlos Eduardo Lagos Campos
60 points

Nuevo abordaje para las neumonías por bacterias resistentes a los antibióticos

NOTICIAS-ETF
8 points

En marcha los estudios para tratar las secuelas de COVID-19 y una recomendación mientras no lleguen

NOTICIAS-ETF
12 points

La vida es bella... si aprendemos a disfrutarla

El diario de Enrique
8 points

De los tigres del Asia a los Leones africanos.

Jorge Luis Rueda Roq
10 points

¿Pueden instalar cámaras de videovigilancia en el trabajo?

MaríaGeek
20 points

Hoy, descanso, es viernes

El diario de Enrique
8 points

Celebra el fin de año con estilo en Residence Inn by Marriott Bogotá

Mariana Ortiz
6 points
SHARE
TWEET
Men who use the drug finasteride to treat an enlarged prostate may experience serious side effects, including worsening erectile dysfunction and decreased testosterone levels leading to hypogonadism, a condition in which there is little to no production of sex hormones.

Prostate drugs make erectile dysfunction worse

Finasteride is also known as proscar and propecia. Men who used tamsulosin—known as Flomax—experienced none of the same adverse side effects.

Considerable controversy exists regarding the severity and persistence of the adverse effects of 5α reductase inhibitors (5α-RIs) such as finasteride. Many investigators believe that the side effects on sexual function affect only a small proportion of treated patients and resolve with continuing treatment.

DROP IN TOTAL TESTOSTERONE
For a new study, published online in the journal Hormone Molecular Biology and Clinical Investigation, researchers studied 470 men who were treated with finasteride and 230 men who received the alpha blocker tamsulosin for their BPH.

Both groups were followed for 45 months and were assessed for improvement of BPH symptoms. Prostate specific antigen and testosterone levels were also measured.

The effects of the drugs on the quality of life were assessed by the Aging Male Symptom scale while the effects of the drugs on erectile function were assessed by the International Index of Erectile Function.

Men treated with finasteride experienced marked and significant gradual decrease in their erectile function and had significant and progressive decline in total testosterone levels while those on the tamsulosin therapy did not.

SEXUAL FUNCTION & OVERALL HEALTH
Both drugs have been proven useful in treatment of lower urinary tract symptoms related to BPH.

“However, 5α reductase inhibitors exert undesirable sexual side effects and, in some cases, these effects are persistent,” says Abdulmaged M. Traish, professor of biochemistry and urology at Boston University School of Medicine.

“Since sexual function is considered an integral part of overall health, it is important that physicians are aware of the adverse side effects of this class of drugs on human health in general and on sexual function in particular. Our study emphasized that the effect on erectile function is a serious concern and needs to be considered more carefully.”

The Boston University School of Medicine’s urology department funded the work.

Fuente: www.futurity.org
SHARE
TWEET
To comment you must log in with your account or sign up!
Featured content