Prostate drugs make erectile dysfunction worse

18.75% credibility
 
Related

Brazil's Ex-Leader, Luiz Inácio Lula da Silva, Is Held for Questioning

Atma
714 points

A mom wrote a heartwarming letter to Hillary Clinton about her dreams for her daughter s future

Atma
658 points



Most recent

Cómo gestionar de forma eficiente las vacaciones de los empleados en una empresa

Mis Noticia
8 points

Reprisal en Colombia por AMC

Avant Garde
12 points

Nueva alarma: El Ártico se derrite, los animales se mueren

Enrique TF-Noticias
18 points

Cinco recomendaciones para optimizar los Centros de Datos

Luisa Fernanda Rozo
14 points

No sé cuándo pasó

Enrique TF-Relatos
14 points

Público colombiano podrá acceder a los paneles de AMC en la Comic Con 2021

Avant Garde
6 points

Promotora Empresarial

charly lakes
40 points

Cuatro palabras para una frase

Enrique TF-Relatos
14 points

Parque Valle de Atriz, un regalo ecologico y ambiental para Pasto.

Pablo Emilio Obando Acosta
16 points

¿Necesitamos más avisos?: El suelo helado ruso, se hunde, el mundo helado se muere

Enrique TF-Noticias
168 points
SHARE
TWEET
Men who use the drug finasteride to treat an enlarged prostate may experience serious side effects, including worsening erectile dysfunction and decreased testosterone levels leading to hypogonadism, a condition in which there is little to no production of sex hormones.

Prostate drugs make erectile dysfunction worse

Finasteride is also known as proscar and propecia. Men who used tamsulosin—known as Flomax—experienced none of the same adverse side effects.

Considerable controversy exists regarding the severity and persistence of the adverse effects of 5α reductase inhibitors (5α-RIs) such as finasteride. Many investigators believe that the side effects on sexual function affect only a small proportion of treated patients and resolve with continuing treatment.

DROP IN TOTAL TESTOSTERONE
For a new study, published online in the journal Hormone Molecular Biology and Clinical Investigation, researchers studied 470 men who were treated with finasteride and 230 men who received the alpha blocker tamsulosin for their BPH.

Both groups were followed for 45 months and were assessed for improvement of BPH symptoms. Prostate specific antigen and testosterone levels were also measured.

The effects of the drugs on the quality of life were assessed by the Aging Male Symptom scale while the effects of the drugs on erectile function were assessed by the International Index of Erectile Function.

Men treated with finasteride experienced marked and significant gradual decrease in their erectile function and had significant and progressive decline in total testosterone levels while those on the tamsulosin therapy did not.

SEXUAL FUNCTION & OVERALL HEALTH
Both drugs have been proven useful in treatment of lower urinary tract symptoms related to BPH.

“However, 5α reductase inhibitors exert undesirable sexual side effects and, in some cases, these effects are persistent,” says Abdulmaged M. Traish, professor of biochemistry and urology at Boston University School of Medicine.

“Since sexual function is considered an integral part of overall health, it is important that physicians are aware of the adverse side effects of this class of drugs on human health in general and on sexual function in particular. Our study emphasized that the effect on erectile function is a serious concern and needs to be considered more carefully.”

The Boston University School of Medicine’s urology department funded the work.

Fuente: www.futurity.org
SHARE
TWEET
To comment you must log in with your account or sign up!
Featured content