Nearly half of women and one-third of men during their lifetime will develop neurological conditions such as Parkinson's disease, dementia or stroke, according to a study.
But Dutch researchers found the lifetime risk can be reduced up to 50 percent -- depending on age -- by following preventive measures. The findings were published Tuesday in the Journal of Neurology Neurosurgery and Psychiatry.
"These findings strengthen the call for prioritizing the focus on preventive interventions at population level which could substantially reduce the burden of common neurological diseases in the aging population," the researchers concluded in the study.
The global costs of dementia, stroke and Parkinson's disease -- among the leading causes of death -- are thought to amount to more than 2 percent of the world's annual economic productivity. And the figure is set to rise steeply as life expectancy continues to increase.
The researchers tracked the neurological health of 12,102 people at least 45 years old taking part in the Rotterdam Study between 1990 and 2016. Around 58 percent of the participants were women, and the median age for everyone was 62. Of the participants, 97 percent had European ancestry and a relatively long life expectancy.
Participants were all free of these diseases and given a thorough health check every four years. The study continued until Jan. 1, 2016, or earlier if they died. During the study, 5,291 people died, including 3,260 not diagnosed with any neurological disease.
Among all participants, 1,489 were diagnosed with dementia, including 80 percent with Alzheimer's disease. A total of 1,285 had a stroke, including 65 percent caused by a blood clot. And 263 were diagnosed with Parkinson's.
Among those diagnosed with any of the three conditions, they were more likely to have high blood pressure, abnormal heart rhythm, high cholesterol and type 2 diabetes at the start of the monitoring period.
The risk of developing them increased substantially with age -- the overall lifetime risk of a 45-year-old developing dementia, Parkinson's or having a stroke was 48 percent in women and 36 percent in men.
Women were at heightened risk of developing dementia compared with men. But men were at substantially higher risk of having a stroke at younger ages than women. At 45, they had similar lifetime risk of a stroke.
And women also were twice as likely as men to be diagnosed with dementia and stroke.
The researchers found delaying the onset of these diseases by 3 to 5 years through preventive measures results in a reduced lifetime risk of 20 percent in 45 year olds and more than 50 percent in those 85 and older.
"Nowadays, preventive measures for primary prevention of cardiovascular disease are tailored to individual lifetime risk estimates," the researchers wrote. "This could inform future prevention programs for common neurological diseases."
A study published last month found the Mediterranean diet may lower the risk of stroke among women. Men, however, did not see similar benefits from the diet, which concentrates on fish, fruits, nuts, vegetables and beans, and avoids meat and dairy products.
"Simple changes in dietary habits may bring a substantial benefit regarding reducing stroke, which remains one of the leading causes of death and disability worldwide," said Dr. Phyo Myint, lead researcher on the diet study.
By Allen Cone
Fuente: www.upi.com
